Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells
Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cruz-Lopez, Olga, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Fruttarolo, Francesca, Heilmann, Jörg, Bermejo, Jaime and Estevez, Francisco (2007) Hybrid molecules containing benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells. Bioorganic & medicinal chemistry letters 17 (10), pp. 2844-2848.Date of publication of this fulltext: 18 Oct 2010 13:23
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| Item type | Article | ||||
| Journal or Publication Title | Bioorganic & medicinal chemistry letters | ||||
| Publisher: | Elsevier | ||||
|---|---|---|---|---|---|
| Volume: | 17 | ||||
| Number of Issue or Book Chapter: | 10 | ||||
| Page Range: | pp. 2844-2848 | ||||
| Date | 2007 | ||||
| Additional Information (public) | CAN 147:95597 28-9 Heterocyclic Compounds (More Than One Hetero Atom) 942267-96-1P; 942267-97-2P; 942267-98-3P; 942267-99-4P; 942268-00-0P Role: PAC (Pharmacological activity), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn. of hybrid mols. contg. benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells); 109-76-2 (1,3-Diaminopropane); 124-09-4 (1,6-Diaminohexane); 196196-26-6; 207845-97-4; 245358-71-8; 294174-53-1; 561318-70-5 Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of hybrid mols. contg. benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells); 942268-01-1P; 942268-02-2P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. of hybrid mols. contg. benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells) | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) | ||||
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| Keywords | Structure-activity relationship (antitumor prepn. of hybrid mols. contg. benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells) Antitumor agents Apoptosis Human Leukemia (prepn. of hybrid mols. contg. benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazole and alpha -bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukemia cells) benzoimidazothiadiazole bromoacryloyl prepn apoptosis inducer myeloid leukemia | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 17234 |
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