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Mammary tumor inhibiting [(1,2-diethyl-1,2-cyclopropanediyl) bis-(phenyl)] diacetates

Schneider, Martin R. ; Schönenberger, Helmut ; Michel, Ralf T.



Abstract

trans-[3,3'-] [84609-01-8] And trans-[4,4'-(1,2-diethyl-1,2-cyclopropanediyl)-bis-(phenyl)] diacetate (I) [84608-97-9] and their 3,3-dichloro derivs. were prepd., and their effect on postmenopausal, hormone-dependent human mammary carcinoma and estrogen receptor affinities in calf uterus cytosol were detd. Meta-substituted compds. exhibited a lower receptor affinity than their para-substituted ...

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