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Effects of Strontium on human osteoblasts extracted from a Cleidocranial Dysplasia patient - In vitro study

Abu Obid Alla, Ahmed I. M. (2010) Effects of Strontium on human osteoblasts extracted from a Cleidocranial Dysplasia patient - In vitro study. PhD, Universität Regensburg.

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Date of publication of this fulltext: 17 Nov 2010 17:24

Abstract (English)

This trial provides valuable impulses and information for pharmacological and clinical research aiming to treat, or at least decrease the severity of Cleidocranial Dysplasia symptoms. Until now, Strontium ranelate was exclusively recognized for treatment of osteoporosis in postmenopausal women or for osteoblast growth stimulation for cell biological laboratory purposes. However, we assume, on the ...


Translation of the abstract (German)

Aufgrund der aus der wissenschaftlichen Literatur bekannten positiven Wirkung von Strontium auf die Knochenbildung entwickelte sich die Überlegung, den Einfluss von Strontium auf Runx2+/- Osteoblasten zu untersuchen. Hierfür wurden Osteoblasten von einem Patienten mit dem Dysostosis cleidocranialis Syndrom entnommen. In dieser Studie verwendeten wir Strontiumchlorid (SrCl2) anstelle von ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:17 November 2010
Referee:Prof. Dr. Peter Proff
Date of exam:8 November 2010
Institutions:Medicine > Lehrstuhl für Kieferorthopädie
Interdisciplinary Subject Network:Not selected
Keywords:Cleidocranial Dysplasia, osteoblast, strontium, Runx2 expression
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:18079
Owner only: item control page


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