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Correlations between chemical structure and antimycotic activity in isomeric hydroxybenzamides

Schönenberger, Helmut, Holzheu-Eckardt, Juergen, Bamann, Eugen and Mehnert, Brigitte (1962) Correlations between chemical structure and antimycotic activity in isomeric hydroxybenzamides. Arzneimittel-Forschung = Drug research 12, pp. 1162-1166.

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Among the hydroxybenzamide compds. tested, the halogenated o-, m-, and p-hydroxybenzanilides are of special importance in view of their high degree of activity. The effect is highly dependent on the position of the hydroxyl group and the halogen atoms. Optimal effects against dermatophytes were found in the compd. with the OH group in ortho position and the halogen substituted groups in 3- and ...


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Item type:Article
Additional Information (public):CAN 59:11353 68 Pharmacodynamics 614-17-5; 6137-53-7; 14180-11-1; 14216-34-3; 90887-50-6 (Derived from data in the 7th Collective Formula Index (1962-1966); 87-17-2 (Salicylanilide); 1697-18-3 (Salicylanilide, 2'-chloro-); 2627-77-2 (Salicylanilide, 4'-bromo-); 3679-63-8 (Salicylanilide, 4'-chloro-); 13410-91-8 (Salicylanilide, 2',3'-dichloro-); 24448-71-3 (Salicylanilide, 3'-chloro-); 37183-28-1 (Salicylanilide, 2',4'-dichloro-); 106480-75-5 (Salicylanilide, 3,4'-dichloro-) (as fungicide); 55-21-0 (Benzamide); 613-93-4 (Benzamide, N-methyl-); 619-57-8 (Benzamide, p-hydroxy-); 2280-99-1 (p-Anisamide, N-butyl-); 3400-22-4 (p-Anisamide, N-methyl-); 3679-68-3 (Benzanilide, 4'-chloro-4-hydroxy-); 7403-41-0 (p-Anisamide, N-ethyl-); 7464-43-9 (p-Anisamide, N-propyl-); 7464-44-0 (p-Anisamide, N-isopropyl-); 7465-88-5 (p-Anisanilide); 7595-61-1 (p-Anisanilide, 4'-chloro-); 10546-70-0 (Benzamide, N-propyl-); 14121-97-2 (Benzanilide, 4-hydroxy-); 27519-68-2 (Benzamide, p-hydroxy-N-propyl-); 27522-79-8 (Benzamide, N-ethyl-p-hydroxy-); 27559-45-1 (Benzanilide, 3-hydroxy-); 36965-04-5 (Benzanilide, 4'-chloro-4-hydroxy-, acetate); 39114-64-2 (Benzamide, N-cyclohexyl-p-hydroxy-); 58748-19-9 (Benzamide, ethoxy-); 60696-49-3 (Benzamide, N-butyl-p-hydroxy-); 62639-20-7 (Benzanilide, 2'-chloro-4-hydroxy-); 73544-81-7 (Benzanilide, 3'-chloro-3-hydroxy-); 73544-82-8 (Benzanilide, 4'-chloro-3-hydroxy-); 79540-62-8 (Benzanilide, 2',3'-dichloro-4-hydroxy-); 83191-67-7 (Benzamide, p-hydroxy-N-isopropyl-); 92044-46-7 (Benzanilide, 2'-chloro-3-hydroxy-); 92044-47-8 (Benzanilide, 3'-chloro-4-hydroxy-); 92433-68-6 (Benzanilide, 2'-chloro-4-hydroxy-, acetate); 92433-69-7 (Benzanilide, 3'-chloro-4-hydroxy-, acetate); 92905-58-3 (Benzanilide, 4'-bromo-3-hydroxy-); 97027-63-9 (Benzanilide, 2',3'-dichloro-3-hydroxy-); 97027-64-0 (Benzanilide, 2',4'-dichloro-3-hydroxy-); 97027-65-1 (Benzanilide, 2',4'-dichloro-4-hydroxy-); 97027-66-2 (Benzanilide, 2',5'-dichloro-3-hydroxy-); 462070-14-0 (Benzanilide, 2',5'-dichloro-4-hydroxy-) (fungicidal activity of)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Identification Number:
Keywords:Nerves (anesthetic effect on) Fungicides or Fungistats (hydroxyaryl amides as)
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:18164
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