Go to content
UR Home

Click Chemistry Based Method for the Preparation of Maleinimide-Type Thiol-Reactive Labels

DOI to cite this document:
Link, Martin ; Li, Xiaohua ; Kleim, Jana ; Wolfbeis, Otto S.
(332kB) - Repository staff only
Date of publication of this fulltext: 18 Mar 2011 06:41


Maleinimides are widely used to label proteins and to derivatize thiols. The so-called click reaction was shown to allow the efficient introduction of the maleinimido group into azido-modified fluorophores (benzoxazines) by reacting them with an alkyne-modified maleinimide to yield new thiol-reactive fluorescent labels 5–7. The reaction proceeds under mild experimental conditions and provides a ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons