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Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine

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DOI to cite this document:
Wagner, R. ; Fliessbach, H. ; Wanner, G. ; Motz, M. ; Niedrig, M. ; Deby, G. ; von Brunn, A. ; Wolf, Hans J.
Date of publication of this fulltext: 12 Apr 2011 07:48


Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives of the HIV-1 group specific core antigen p55 gag was assayed and compared dependent on various expression systems: recombinant bacteria, vaccinia- and baculoviruses were established encoding the entire core protein p55 either in its authentic ...


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