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Immunological reactivity of a human immunodeficiency virus type I derived peptide representing a consensus sequence of the GP120 major neutralizing region V3

URN to cite this document:
urn:nbn:de:bvb:355-epub-204405
Wagner, R. ; Modrow, Susanne ; Böltz, T. ; Fliessbach, H. ; Niedrig, M. ; von Brunn, A. ; Wolf, Hans J.
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Date of publication of this fulltext: 12 Apr 2011 07:40


Abstract

To reduce the opportunities for human immunodeficiency virus type 1 (HIV-1) to evade vaccine induced immunity, the development of subunit vaccines must focus on the characterization of immunogenic epitopes, which are major targets for the immune system. The most dominant site for elicitation of neutralising immune response is located on the external envelope glycoprotein gp120 within the third ...

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