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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-204512
- DOI to cite this document:
- 10.5283/epub.20451
Abstract (German)
In neueren Studien wurden verschiedene Assoziationen genetischer Varianten der Toll-like-Rezeptoren (TLRs)mit dem Outcome nach Nierentransplantation beschrieben. Heute sind mehr als 10 humane TLRs mit unterschiedlichen Effekten auf das Transplantat-Outcome bekannt. Dabei stellen MAL (MyD88 adapter like) und MyD88 (myelolid differentiation factor 88) zentrale Schlüsselmoleküle dar. Genetische ...

Translation of the abstract (English)
In recent studies different associations of genetic variations in toll like receptors (TLRs) with kidney transplant outcomes were described. To date more than 10 human TLRs are known with various effects on transplant outcome. Central key molecules are MAL (MyD88 adapter like) and myD88 (myeloid differentiation factor 88). Genetic variations in this signaling molecules provide an elegant method ...
