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Epstein-Barr virus-positive recipient type B-cells survive in a "complete chimera" after allogeneic bone-marrow transplantation

URN to cite this document:
urn:nbn:de:bvb:355-epub-205249
Gerhartz, H. H. ; Mittermüller, J. ; Raghavachar, A. ; Schmetzer, H. ; Clemm, C. ; Kolb, H. J. ; Bartram, C. C. ; Wolf, Hans J.
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Date of publication of this fulltext: 15 Apr 2011 09:11


Abstract

Latency of Epstein-Barr virus infection may be generated by surviving immortalized B cells or by continuous re-infection. EBV-positive B-cell tumors have been found following bone-marrow transplantation (BMT) and were of donor type in the few cases investigated. We established a B-cell line from the bone marrow of a patient in complete remission following allogeneic BMT for aplastic anemia 18 ...

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