Cloning of a novel malignant melanoma-derived growth-regulatory protein, MIA

URN to cite this document:: urn:nbn:de:bvb:355-epub-209932
DOI to cite this document:: 10.5283/epub.20993

Blesch, A. ; Bosserhoff, Anja-Katrin ; Apfel, R. ; Behl, C. ; Hessdoerfer, B. ; Schmitt, A. ; Jachimczak, P. ; Lottspeich, F. ; Buettner, R. ; Bogdahn, Ulrich

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Date of publication of this fulltext: 07 Jun 2011 06:22

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Abstract

Growth and progression of malignant melanoma cells is influenced by a complex network of growth-stimulating and -inhibiting factors produced by both the tumor cells and the local environment. Here we report the purification and molecular cloning of a novel growth regulating protein, designated melanoma inhibitory activity (MIA) and provide a preliminary functional characterization. MIA is ...