Go to content
UR Home

Biochemical and functional studies on mouse ficolin-B, a novel pattern recognition molecule of the innate immune system

URN to cite this document:
urn:nbn:de:bvb:355-epub-225621
Elumalai, Preetham
Date of publication of this fulltext: 16 Nov 2011 10:02


Abstract (English)

Ficolins are members of the collectin family of proteins which in human and mice are able to recognize pathogen associated molecular patterns (PAMPs) on microbial surfaces. Ficolins trigger the activation of the innate immune system by initiating the complement cascade in serum upon binding to their specific PAMPs. Our group recently published the first observation on the cellular localization of ...

plus

Translation of the abstract (German)

Ficoline sind Mitglieder der Collectin-Proteinfamilie, die in Mensch und Maus Pathogen-assoziierte molekulare Muster (PAMP) auf Oberflächen erkennen. Ficoline starten das angeborene Immunsystem, indem sie im Serum nach Bindung an spezifische PAMP die Complement-Kaskade aktivieren. Unsere Arbeitsgruppe zeigte als erste, dass Maus-Ficolin-B intrazellulär lokalisiert ist. Im Gegensatz zum humanen ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons