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Membrane functionalisation using polyrotaxanes with amphiphilic cyclodextrins

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Bauer, Martin
Date of publication of this fulltext: 08 May 2012 08:25

Abstract (English)

This work is aimed at the design and characterisation of a new family of tethered ligands, called sliding tethered ligands (STLs). They are based on topological complexes between polymers and amphiphilic cyclodextrins (CDs), which can be inserted into phospholipid membranes. At first we investigate the membrane insertion properties of amphiphilic cholesteryl CD derivatives, which are suitable ...


Translation of the abstract (German)

Ziel dieser Arbeit ist die Synthese und Charakterisierung einer neuen Gruppe von Liganden, sog. “Sliding Tethered Ligands” (STLs). STLs basieren auf topologischen Komplexen zwischen Polymeren und amphiphilen Cyclodextrinen (CDs), die in Phospholipidmembranen eingebaut werden können. Zunächst werden amphiphile Cholesteryl-CDDerivate untersucht, insbesondere bezüglich ihrer Fähigkeit, sich in ...


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