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Membrane functionalisation using polyrotaxanes with amphiphilic cyclodextrins

Bauer, Martin (2012) Membrane functionalisation using polyrotaxanes with amphiphilic cyclodextrins. PhD, Universität Regensburg.

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Date of publication of this fulltext: 08 May 2012 08:25

Abstract (English)

This work is aimed at the design and characterisation of a new family of tethered ligands, called sliding tethered ligands (STLs). They are based on topological complexes between polymers and amphiphilic cyclodextrins (CDs), which can be inserted into phospholipid membranes. At first we investigate the membrane insertion properties of amphiphilic cholesteryl CD derivatives, which are suitable ...

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Translation of the abstract (German)

Ziel dieser Arbeit ist die Synthese und Charakterisierung einer neuen Gruppe von Liganden, sog. “Sliding Tethered Ligands” (STLs). STLs basieren auf topologischen Komplexen zwischen Polymeren und amphiphilen Cyclodextrinen (CDs), die in Phospholipidmembranen eingebaut werden können. Zunächst werden amphiphile Cholesteryl-CDDerivate untersucht, insbesondere bezüglich ihrer Fähigkeit, sich in ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:8 May 2012
Referee:Prof. Dr. Werner Kunz and Prof. Dr. Jürgen Rühe and Prof. Dr. Gerhard Wenz
Date of exam:4 November 2011
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry)
Keywords:amphiphilic cyclodextrins, phospholipid model membranes, membrane modification, polyrotaxanes, sliding tethered ligands, ligand-receptor interactions
Dewey Decimal Classification:500 Science > 530 Physics
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:23003
Owner only: item control page

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