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Large-Scale Candidate Gene Analysis of HDL Particle Features

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Kaess, B. M. ; Tomaszewski, M. ; Braund, P. S. ; Stark, K. ; Rafelt, S. ; Fischer, Marcus ; Hardwick, R. ; Nelson, C. P. ; Debiec, R. ; Huber, Fritz ; Kremer, Werner ; Kalbitzer, Hans Robert
Date of publication of this fulltext: 17 Feb 2012 08:52


Background: HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore assessed HDL particles by NMR spectroscopy and conducted a large-scale candidate gene association analysis. Methodology/Principal ...


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