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New fluorescent probes for ATP and other phosphates

Lang, Thomas (2012) New fluorescent probes for ATP and other phosphates. PhD, Universität Regensburg.

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Date of publication of this fulltext: 14 Jun 2012 06:02

Abstract (English)

Phosphate-sensitive probes have been synthesized and characterized. The focus was on the (bio)phosphates ATP, ADP, AMP, cAMP, GTP, GDP, GMP, cGMP, Pi and PPi. One design is utilizing the quenching of APTS or HPTS by viologen derivatives which is reversed upon addition of phosphates. Three viologens were tested for their applicability. The compound TEAPB in combination with HPTS yielded the most ...

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Translation of the abstract (German)

Phosphatsensitive Sonden wurden synthetisiert und charakterisiert. Der Fokus lag dabei auf Biophosphaten ATP, ADP, AMP, cAMP, GTP, GDP, GMP, cGMP, Pi und PPi. Eine Messanordnung macht sich das Quenchen von APTS oder HPTS durch Viologenderivate zu nutzen welches bei Zugabe von Posphaten umgekehrt wird. Drei Viologene wurden auf ihre Verwendbarkeit getestet. Die Verbindung TEAPB in Kombination mit ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:14 June 2012
Referee:Prof. Dr. Otto S. Wolfbeis
Date of exam:6 June 2012
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Keywords:detection of phosphate, fluorescence, NIR
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:24846
Owner only: item control page

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