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Characteristics of “Tip-DCs and MDSCs” and their potential role in leishmaniasis

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Schmid, Maximilian ; Wege, Anja K. ; Ritter, Uwe
License: Creative Commons Attribution Non-commercial 3.0
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Date of publication of this fulltext: 07 Sep 2012 07:05


Since the first description of dendritic cells (DCs) by Steinman and Cohn (1973), the myeloid lineage of leukocytes was investigated intensively. Nowadays it is obvious that myeloid cells, especially DCs, are crucial for the adaptive and innate immune response against intracellular pathogens such as Leishmania major parasites. Based on the overlapping expression of molecules that were commonly ...


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