microRNAs associated with the different human Argonaute proteins

URN to cite this document:: urn:nbn:de:bvb:355-epub-265544
DOI to cite this document:: 10.5283/epub.26554

Dueck, Anne ; Ziegler, Christian ; Eichner, Alexander ; Berezikov, Eugene

; Meister, Gunter

Preview

License: Creative Commons: Attribution-Noncommercial 3.0
PDF - Published Version
(8MB)

Date of publication of this fulltext: 24 Oct 2012 10:27

Alternative links to fulltext:DOI

Details

Preview

Indexed in

Export bibliographical data

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs that function in literally all cellular processes. miRNAs interact with Argonaute (Ago) proteins and guide them to specific target sites located in the 3'-untranslated region (3'-UTR) of target mRNAs leading to translational repression and deadenylation-induced mRNA degradation. Most miRNAs are processed from hairpin-structured precursors by the ...