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Effects of psychosocial stress on retinal neurodegeneration

Forkwa Kieran, Tembei (2012) Effects of psychosocial stress on retinal neurodegeneration. PhD, Universität Regensburg.

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Date of publication of this fulltext: 03 Dec 2012 09:07

Abstract (English)

Vision loss in hereditary retinal degeneration or glaucoma is caused by apoptotic death of photoreceptors or retinal ganglion cells (RGC), respectively. In animal models of both diseases, treatment with glucocorticoids (GC) has been shown to protect against neuronal cell death. We could show that 10 h of psychosocial stress induced by chronic subordinate colony housing (CSC) protects mouse ...

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Translation of the abstract (German)

Sehverlust bei erblichen Netzhautdegenerationen oder beim Glaukom wird durch Apoptose von Photorezeptoren oder retinalen Ganglienzellen (RGC) hervorgerufen. Tiermodelle beider Krankheiten zeigen, dass Glucocorticoide (GC) protektive Effekte auf den neuronalen Untergang zeigen. Wir konnten beobachten, dass 10h psychosozialer Stress, induziert durch chronisch subordinierte Koloniehaltung (CSC), der ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:3 December 2012
Referee:Prof. Dr. Ernst Tamm
Date of exam:14 November 2012
Institutions:Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Humananatomie und Embryologie > Prof. Dr. Ernst Tamm
Keywords:psychosocial stress, glucocorticoids, neurodegeneration, apoptosis, neuro protection
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:26819
Owner only: item control page

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