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Role of calcium ions in the pressure control of renin secretion from the kidneys

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Scholz, Holger ; Hamann, Marlies ; Götz, Karl-Heinz ; Kurtz, Armin
Date of publication of this fulltext: 05 Dec 2012 10:22


In this study we examined the role of calcium ions in the control of renin release by the renal artery pressure. For this purpose renin secretion rates (RSR) were measured in isolated rat kidneys perfused at pressures of 140, 100, 80 and 40 mmHg (19, 13, 11, 5 kPa) with media containing either 1.5 mmol/l ("normal") or zero calcium concentrations (calcium-free perfusate with 0.5 mmol/l EGTA). At ...


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