Role of calcium ions in the pressure control of renin secretion from the kidneys

URN to cite this document:: urn:nbn:de:bvb:355-epub-269225
DOI to cite this document:: 10.5283/epub.26922

Scholz, Holger ; Hamann, Marlies ; Götz, Karl-Heinz ; Kurtz, Armin

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Date of publication of this fulltext: 05 Dec 2012 10:22

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Abstract

In this study we examined the role of calcium ions in the control of renin release by the renal artery pressure. For this purpose renin secretion rates (RSR) were measured in isolated rat kidneys perfused at pressures of 140, 100, 80 and 40 mmHg (19, 13, 11, 5 kPa) with media containing either 1.5 mmol/l ("normal") or zero calcium concentrations (calcium-free perfusate with 0.5 mmol/l EGTA). At ...