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Antiproliferative and Erythroid Differentiation of Piperazine and Triphenyl Derivatives Against K-562 Human Chronic Myelogenous Leukemia

Saab, Antoine Michael ; Dobmeier, Michael ; König, Burkhard ; Fabri, Enrica ; Finotti, Alessia ; Borgatti, Monica ; Lampronti, Ilaria ; Bernardi, Francesco ; Efferth, Thomas ; Gambari, Roberto



Abstract

Five piperazine derivatives (S)-4-benzyl-1-(4-bromo-3-methylphenyl)-2 methylpiperazine (A), (S)-1-benzyl-3-isobutylpiperazine-2,5-dione (B), (S)-1-benzyl-3 methylpiperazine-2,5-dione (C), (S)-1,3-dibenzylpiperazine-2,5-dione (D), (E)-1-(3-methyl 4-((E)-3-(2-methylpropylidene) piperazin-1-yl) phenyl)-2-(2 methylpropylidene) piperazine (E) and triphenyl derivative ammonium ...

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