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A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: the COMBATAC trial

Glockzin, Gabriel, Rochon, Justine, Arnold, Dirk, Lang, Sven A., Klebl, Frank, Zeman, Florian, Koller, Michael, Schlitt, Hans J. and Piso, Pompiliu (2013) A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: the COMBATAC trial. BMC Cancer 13, p. 67.

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Date of publication of this fulltext: 03 Sep 2013 07:30

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Abstract

BACKGROUND: Peritoneal carcinomatosis is regarded as a common sign of advanced tumor stage, tumor progression or local recurrence of appendiceal and colorectal cancer and is generally associated with poor prognosis. Although survival of patients with advanced stage CRC has markedly improved over the last 20 years with systemic treatment, comprising combination chemotherapy +/- monoclonal ...

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Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Chirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
23391248PubMed ID
10.1186/1471-2407-13-67DOI
Classification:
NotationType
Adenocarcinoma/therapyMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Appendiceal Neoplasms/therapyMESH
Chemotherapy, AdjuvantMESH
Chemotherapy, Cancer, Regional Perfusion/adverse effectsMESH
Colorectal Neoplasms/therapyMESH
Digestive System Surgical Procedures/adverse effectsMESH
Disease-Free SurvivalMESH
Feasibility StudiesMESH
GermanyMESH
HumansMESH
Hypothermia, Induced/adverse effectsMESH
Metastasectomy/adverse effectsMESH
Peritoneal Neoplasms/therapyMESH
Prospective StudiesMESH
Proto-Oncogene Proteins/geneticsMESH
Quality of LifeMESH
Research DesignMESH
Sample SizeMESH
Time FactorsMESH
Treatment OutcomeMESH
ras Proteins/geneticsMESH
Keywords:Cytoreductive surgery, HIPEC, Perioperative chemotherapy, Cetuximab, Colorectal cancer, Peritoneal carcinomatosis
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28774
Owner only: item control page

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