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Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: Impact of exogenous Neuropeptide Y

Dietrich, Peter (2013) Dysbalance in sympathetic neurotransmitter release and action in cirrhotic rats: Impact of exogenous Neuropeptide Y. PhD, Universität Regensburg.

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Date of publication of this fulltext: 02 Dec 2013 15:45

Abstract (English)

Background & Aims: Splanchnic vasodilation is an essential dis- turbance in portal hypertension. Increased systemic sympathetic nerve activity is well known, but potential corresponding vascu- lar desensitization is incompletely characterized. Release of splanchnic sympathetic neurotransmitters noradrenaline (NA) and co-transmitter neuropeptide Y (NPY) remains to be eluci- dated. Finally, the ...

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Translation of the abstract (German)

Hintergrund: Bei portalem Hypertonus und den assoziierten hämodynamischen Störungen ist splanchnische arterielle Vasodilatation pathophysiologisch entscheidend. Die kompensatorisch gesteigerte Aktivität des sympathischen Nervensystems ist bekannt. Ziele: Es ist unklar, ob dies zu vaskulärer Desensibilisierung führt. Die Rolle von endogen freigesetzten Vasokonstriktoren wie Noradrenalin (NA) und ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:2 December 2013
Referee:Prof. Dr. Reiner Wiest
Date of exam:15 October 2013
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Keywords:Portal hypertension, sympathethic nervous system, liver cirrhosis, Leberzirrhose, portale Hypertension, sympathisches Nervensystem
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29088
Owner only: item control page

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