Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

Article

Bogdahn, Ulrich, Hau, Peter, Stockhammer, G., Venkataramana, N. K., Mahapatra, A. K., Suri, A., Balasubramaniam, A., Nair, S., Oliushine, V., Parfenov, V., Poverennova, I., Zaaroor, M., Jachimczak, P., Ludwig, S., Schmaus, S., Heinrichs, H. and Schlingensiepen, K. H. (2011) Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro-oncology 13 (1), pp. 132-142.

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• Medicine > Lehrstuhl für Neurologie

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Details

Item type	Article
Journal or Publication Title	Neuro-oncology
Publisher	OXFORD UNIV PRESS INC
Place of Publication	CARY
Volume	13
Number of Issue or Book Chapter	1
Page Range	pp. 132-142
Date	2011
Date of publication	09 Dec 2013 11:08
Additional Information (public)	Trabedersen Glioma Study Group
Institutions	Medicine > Lehrstuhl für Neurologie
Identification Number	Value Type 21558078 PubMed ID 10.1093/neuonc/noq142 DOI
Classification	Notation Type Adult MESH Antineoplastic Agents/therapeutic use MESH Brain Neoplasms/pathology MESH Female MESH Glioblastoma/pathology MESH Humans MESH International Agencies MESH Male MESH Middle Aged MESH Neoplasm Recurrence, Local/pathology MESH Oligodeoxyribonucleotides/therapeutic use MESH Survival Rate MESH Thionucleotides/therapeutic use MESH Transforming Growth Factor beta2/antagonists & inhibitors MESH Treatment Outcome MESH
Keywords	RECURRENT MALIGNANT GLIOMA; GROWTH-FACTOR BETA-2; PROGNOSTIC-FACTORS; BRAIN-TUMORS; ADJUVANT TEMOZOLOMIDE; CLINICAL-TRIALS; TGF-BETA; GLIOBLASTOMA; IMMUNOSUPPRESSION; CONCOMITANT; anaplastic astrocytoma; antisense oligonucleotide; convection-enhanced delivery; glioblastoma multiforme; recurrent or refractory high-grade glioma; targeted therapy; temozolomide; trabedersen; transforming growth factor beta 2
Dewey Decimal Classification	600 Technology > 610 Medical sciences Medicine
Status	Published
Refereed	Yes, this version has been refereed
Created at the University of Regensburg	Unknown
Item ID	29178

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