Go to content
UR Home

Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05)

Grauer, Oliver, Pascher, Christina, Hartmann, Christian, Zeman, Florian, Weller, Michael, Proescholdt, Martin A., Brawanski, Alexander, Pietsch, Thorsten, Wick, Wolfgang, Bogdahn, Ulrich and Hau, Peter (2011) Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05). Journal of neuro-oncology 104 (3), pp. 801-809.

Full text not available from this repository.

at PubMed

at publisher (via DOI)


Abstract

The objective of this prospective, monocentric phase-II pilot study was to evaluate toxicity and efficacy of neoadjuvant temozolomide (TMZ) and 13-cis retinoic acid (13-cRA) treatment in patients with newly diagnosed anaplastic gliomas after total or subtotal tumor resection. The primary endpoint of the study was median progression-free survival (PFS). Secondary endpoints were toxicity and PFS ...

plus


Export bibliographical data



Item type:Article
Date:2011
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
21373969PubMed ID
10.1007/s11060-011-0548-yDOI
Classification:
NotationType
Administration, OralMESH
AdolescentMESH
AdultMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Brain Neoplasms/mortalityMESH
DNA Modification Methylases/geneticsMESH
DNA Repair Enzymes/geneticsMESH
Dacarbazine/therapeutic useMESH
Disease-Free SurvivalMESH
Drug Administration ScheduleMESH
FemaleMESH
Glioma/mortalityMESH
HumansMESH
Isocitrate Dehydrogenase/geneticsMESH
MaleMESH
Middle AgedMESH
Mutation/geneticsMESH
Prospective StudiesMESH
Retinaldehyde/therapeutic useMESH
Tumor Suppressor Proteins/geneticsMESH
Young AdultMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29180
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons