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18F-FET-PET-based dose painting by numbers with protons

Rickhey, Mark ; Morávek, Zdenek ; Eilles, Christoph ; Koelbl, Oliver ; Bogner, Ludwig



Abstract

Purpose: To investigate the potential of (18)F-fluoroethyltyrosine-positron emission tomography-((18)F-FET-PET-)based dose painting by numbers with protons. Material and Methods: Due to its high specificity to brain tumor cells, FET has a high potential to serve as a target for dose painting by numbers. Biological image-based dose painting might lead to an inhomogeneous dose prescription. For ...

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