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Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs)

Drees, Johannes (2013) Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). PhD, Universität Regensburg.

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Date of publication of this fulltext: 17 Dec 2013 10:35

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Abstract (English)

Dental stem cells, especially dental follicle cells (DFCs) as precursor cells for the periodontium have interesting prospects for regenerative dentistry. During periodontitis, butyrate as a bacterial metabolite and inflammatory agent is often found in millimolar concentrations in periodontal pockets. This study evaluates the effects of butyrate on the proliferation and osteogenic differentiation ...

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Translation of the abstract (German)

Dentale Stammzellen, insbesondere dentale Follikelzellen (DFCs) als Vorläuferzellen des Parodonts besitzen vielversprechende Aussichten für regenerative Therapieansätze. Butyrat als bakterieller Metabolit und inflammatorisch aktive Substanz findet sich oftmals in millimolarer Konzentration in aktiven parodontalen Taschen wieder. Diese Studie befasst sich mit dem Einfluss von Butyrat auf den ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:17 December 2013
Referee:PD Dr. Christian Morsczeck
Date of exam:12 December 2013
Institutions:Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Identification Number:
ValueType
10.1007/s10266-013-0117-2DOI
23836050PubMed ID
Keywords:Dental follicle cells, butyrate, osteogenic differentiation, alkaline phosphatase, proliferation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29228
Owner only: item control page

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