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RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study

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Beier, Christoph P. ; Schmid, Christina ; Gorlia, Thierry ; Kleinletzenberger, Christine ; Beier, Dagmar ; Grauer, Oliver ; Steinbrecher, Andreas ; Hirschmann, Birgit ; Brawanski, Alexander ; Dietmaier, Christopher ; Jauch-Worley, Tanja ; Kölbl, Oliver ; Pietsch, Torsten ; Proescholdt, Martin A. ; Rümmele, Petra ; Muigg, Armin ; Stockhammer, Günther ; Hegi, Monika ; Bogdahn, Ulrich ; Hau, Peter
Date of publication of this fulltext: 16 Jan 2014 11:37


Together, the investigated combination is tolerable and feasible. Neither the addition of PEG-Dox nor the prolonged administration of Temozolomide resulted in a meaningful improvement of the patient's outcome as compared to the EORTC26981/NCIC-CE.3 data.

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