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RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study

Beier, Christoph P., Schmid, Christina, Gorlia, Thierry, Kleinletzenberger, Christine, Beier, Dagmar, Grauer, Oliver, Steinbrecher, Andreas, Hirschmann, Birgit, Brawanski, Alexander, Dietmaier, Christopher, Jauch-Worley, Tanja, Kölbl, Oliver, Pietsch, Torsten, Proescholdt, Martin A., Rümmele, Petra, Muigg, Armin, Stockhammer, Günther, Hegi, Monika, Bogdahn, Ulrich and Hau, Peter (2009) RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study. BMC cancer 9, p. 308.

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Abstract

Together, the investigated combination is tolerable and feasible. Neither the addition of PEG-Dox nor the prolonged administration of Temozolomide resulted in a meaningful improvement of the patient's outcome as compared to the EORTC26981/NCIC-CE.3 data.


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Item type:Article
Date:2009
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
17664483PubMed ID
10.1186/1471-2407-9-308DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Central Nervous System Neoplasms/radiotherapyMESH
Combined Modality TherapyMESH
Dacarbazine/analogs & derivativesMESH
Doxorubicin/analogs & derivativesMESH
Drug Administration ScheduleMESH
Drug Therapy, CombinationMESH
Drug-Related Side Effects and Adverse ReactionsMESH
FemaleMESH
Glioblastoma/radiotherapyMESH
HumansMESH
MaleMESH
Middle AgedMESH
Polyethylene Glycols/adverse effectsMESH
Young AdultMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29307
Owner only: item control page

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