Go to content
UR Home

Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair

Schreml, Stephan, Meier, Robert Johannes, Kirschbaum, Michael, Kong, Su-Chii, Gehmert, Sebastian, Felthaus, Oliver, Küchler, Sarah, Sharpe, Justin R., Wöltje, Kerstin, Weiß, Katharina, Albert, Markus, Seidl, Uwe, Schröder, Josef, Morsczeck, Christian, Prantl, Lukas, Duschl, Claus, Pedersen, Stine F., Gosau, Martin, Breneburg, Mark, Wolfbeis, Otto S., Landthaler, Michael and Babilas, Philipp (2014) Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair. Theranostics 4 (7), pp. 721-735.

[img]
Preview
License: Creative Commons Attribution Non-commercial No Derivatives 3.0
PDF - Published Version
Download (2MB)
Date of publication of this fulltext: 22 May 2014 12:06

at publisher (via DOI)

Other URL: http://www.thno.org/v04p0721.htm


Abstract

Wound repair is a quiescent mechanism to restore barriers in multicellular organisms upon injury. In chronic wounds, however, this program prematurely stalls. It is known that patterns of extracellular signals within the wound fluid are crucial to healing. Extracellular pH (pHe) is precisely regulated and potentially important in signaling within wounds due to its diverse cellular effects. ...

plus


Export bibliographical data



Item type:Article
Date:30 April 2014
Institutions:Medicine > Lehrstuhl für Dermatologie und Venerologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.7150/thno.9052DOI
Keywords:fluorescence imaging, wound healing, cell migration, gradient sensing, proton transporters
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:30016
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons