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Unsupervised meta-analysis on diverse gene expression datasets allows insight into gene function and regulation

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Engelmann, Julia C. ; Schwarz, Roland ; Blenk, Steffen ; Friedrich, Torben ; Seibel, Philipp N. ; Dandekar, Thomas ; Müller, Tobias
License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 20 Aug 2014 08:26


Over the past years, microarray databases have increased rapidly in size. While they offer a wealth of data, it remains challenging to integrate data arising from different studies. Here we propose an unsupervised approach of a large-scale meta-analysis on Arabidopsis thaliana whole genome expression datasets to gain additional insights into the function and regulation of genes. Applying kernel ...


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