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A circulating microRNA profile is associated with late-stage neovascular age-related macular degeneration

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Grassmann, Felix ; Schoenberger, Peter G. A. ; Brandl, Caroline ; Schick, Tina ; Hasler, Daniele ; Meister, Gunter ; Fleckenstein, Monika ; Lindner, Moritz ; Helbig, Horst ; Fauser, Sascha ; Weber, Bernhard H. F.
License: Creative Commons: Attribution 3.0
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Date of publication of this fulltext: 11 Sep 2014 13:20


Age-related macular degeneration (AMD) is the leading cause of severe vision impairment in Western populations over 55 years. A growing number of gene variants have been identified which are strongly associated with an altered risk to develop AMD. Nevertheless, gene-based biomarkers which could be dysregulated at defined stages of AMD may point toward key processes in disease mechanism and thus ...


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