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Platelet-derived extracellular vesicles in plateletpheresis concentrates as a quality control approach

URN to cite this document:
urn:nbn:de:bvb:355-epub-307964
Black, Anne
Date of publication of this fulltext: 02 Oct 2014 15:28


Abstract (English)

Platelet-derived extracellular vesicles (PL-EVs) constitute the major part of circulating EVs in blood. They are also present in platelet concentrates (PCs) and may influence the quality of PCs as recent reports implicate significant pro-thrombotic and pro-coagulant activities of PL-EVs. The aim of the present study was to analyze PC-derived PL-EVs and to correlate them with standard quality ...

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Translation of the abstract (German)

Im zirkulierenden Blut des Menschen stammt der überwiegende Anteil der extrazellulären Vesikel (EVs) von Thrombozyten und Megakaryozyten ab. Die thrombozytären EVs kommen ebenfalls in Apheresekonzentraten, wie beispielsweise Thrombozytapheresekonzentraten (TKs) vor und beeinflussen die Qualität der Blutprodukte auf unterschiedliche, noch nicht umfassend geklärte Weise. Unter anderem haben ...

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