Wagner, Ralf, Bruun, Tim-Henrik, Mühlbauer, Katharina, Benen, Thomas and Kliche, Alexander (2014) A mammalian cell based FACS-panning platform for the selection of HIV-1 envelopes for vaccine development. PLoS ONE 9 (10), e109196.
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Abstract
An increasing number of broadly neutralizing monoclonal antibodies (bnMAb) against the HIV-1 envelope (Env) protein has been discovered recently. Despite this progress, vaccination efforts with the aim to re-elicit bnMAbs that provide protective immunity have failed so far. Herein, we describe the development of a mammalian cell based FACS-panning method in which bnMAbs are used as tools to ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 3 October 2014 | ||||
| Institutions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene | ||||
| Projects: | Open Access Publizieren (DFG) | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 30861 |
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