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A mammalian cell based FACS-panning platform for the selection of HIV-1 envelopes for vaccine development

Wagner, Ralf, Bruun, Tim-Henrik, Mühlbauer, Katharina, Benen, Thomas and Kliche, Alexander (2014) A mammalian cell based FACS-panning platform for the selection of HIV-1 envelopes for vaccine development. PLoS ONE 9 (10), e109196.

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Date of publication of this fulltext: 10 Oct 2014 11:07

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Other URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0109196


Abstract

An increasing number of broadly neutralizing monoclonal antibodies (bnMAb) against the HIV-1 envelope (Env) protein has been discovered recently. Despite this progress, vaccination efforts with the aim to re-elicit bnMAbs that provide protective immunity have failed so far. Herein, we describe the development of a mammalian cell based FACS-panning method in which bnMAbs are used as tools to ...

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Item type:Article
Date:3 October 2014
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0109196DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30861
Owner only: item control page

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