Regulation of Connective Tissue Growth Factor Expression Influences the Cell Viability In Human Trabecular Meshwork Cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-313629
DOI to cite this document:: 10.5283/epub.31362

Fuchsdorfer, Rudolf ; Tamm, Ernst R. ; Küspert, Sabrina Angela

; Braunger, Barbara Maria

; Junglas, Benjamin

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Date of publication of this fulltext: 26 Feb 2015 08:01

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Abstract

Connective tissue growth factor (CTGF) induces extracellular matrix (ECM) synthesis and contractility in human trabecular meshwork (HTM) cells. Both processes are involved in the pathogenesis of primary open-angle glaucoma. To date, little is known about regulation and function of CTGF expression in the trabecular meshwork (TM). Therefore, we analysed the effects of different aqueous humour ...