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Regulation of Connective Tissue Growth Factor Expression Influences the Cell Viability In Human Trabecular Meshwork Cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-313629
Fuchsdorfer, Rudolf ; Tamm, Ernst R. ; Küspert, Sabrina Angela ; Braunger, Barbara Maria ; Junglas, Benjamin
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Date of publication of this fulltext: 26 Feb 2015 08:01


Abstract

Connective tissue growth factor (CTGF) induces extracellular matrix (ECM) synthesis and contractility in human trabecular meshwork (HTM) cells. Both processes are involved in the pathogenesis of primary open-angle glaucoma. To date, little is known about regulation and function of CTGF expression in the trabecular meshwork (TM). Therefore, we analysed the effects of different aqueous humour ...

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