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Regulation der Überexpression des Keratinozytenwachstumsfaktors in fibrosierenden Erkrankungen der Haut

Schellenberger, Christiane (2016) Regulation der Überexpression des Keratinozytenwachstumsfaktors in fibrosierenden Erkrankungen der Haut. PhD, Universität Regensburg.

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Date of publication of this fulltext: 10 Oct 2016 05:43

Abstract (German)

Fibrosierende Erkrankungen, wie das Keloid, die zirkumskripte und die systemische Sklerodermie, sind durch eine erhöhte Kollagenproduktion aktivierter dermaler Fibroblasten gekennzeichnet. Trotz vielgestaltiger Krankheitsbilder wird die pathologische Fibroblastenaktivierung als der entscheidenende pathogenetische Mechanismus angesehen. Epithelial-mesenchymale Interaktionen zwischen den ...

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Translation of the abstract (English)

Fibrosing connective tissue disorders of the skin, like keloid, systemic and localized scleroderma, are characterized by an elevated collagen production by activated dermal fibroblasts. Pathologic fibroblast activation and in particular epithelial-mesenchymal crosstalk between keratinocytes and fibroblasts seems to be the central pathogenetic mechanism. Canady and colleagues could identify a ...

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Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:10 October 2016
Referee:Prof. Dr. Anja Katrin Boßerhoff
Date of exam:9 October 2015
Institutions:Medicine > Lehrstuhl für Pathologie
Keywords:dermale Fibrose, Keratinozytenwachstumsfaktor, c-jun
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32548
Owner only: item control page

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