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K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated Manner

Wölfle, Giesela, Zundler, Sebastian, Caioni, Massimiliano, Müller, Martina, Strauch, Ulrike and Kunst, Claudia (2016) K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated Manner. PLoS ONE 11 (1), pp. 1-27.

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Date of publication of this fulltext: 29 Feb 2016 16:58

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147736


Abstract

Background Potassium channels have been shown to determine wound healing in different tissues, but their role in intestinal epithelial restitution–the rapid closure of superficial wounds by intestinal epithelial cells (IEC)–remains unclear. Methods In this study, the regulation of IEC migration by potassium channel modulation was explored with and without additional epidermal growth factor (EGF) ...

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Item type:Article
Date:29 January 2016
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pone.0147736DOI
Article ID: e0147736DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33444
Owner only: item control page

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