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Identification of gene expression patterns critically involved in experimental autoimmune encephalomyelitis and multiple sclerosis

URN to cite this document:
urn:nbn:de:bvb:355-epub-345126
DOI to cite this document:
10.5283/epub.34512
Weissert, Robert ; Herrmann, Martin M. ; Barth, Silvia ; Greve, Bernhard ; Schumann, Kathrin M. ; Bartels, Andrea
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Date of publication of this fulltext: 02 Sep 2016 14:09


Abstract

After encounter with a central nervous system (CNS)-derived autoantigen, lymphocytes leave the lymph nodes and enter the CNS. This event leads only rarely to subsequent tissue damage. Genes relevant to CNS pathology after cell infiltration are largely undefined. Myelin-oligodendrocyte-glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple ...

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