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Progression of Late-Onset Stargardt Disease

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Lambertus, Stanley ; Lindner, Moritz ; Bax, Nathalie M. ; Mauschitz, Matthias M. ; Nadal, Jennifer ; Schmid, Matthias ; Schmitz-Valckenberg, Steffen ; den Hollander, Anneke I. ; Weber, Bernhard H. F. ; Holz, Frank G. ; van der Wilt, Gert Jan ; Fleckenstein, Monika ; Hoyng, Carel B.
Date of publication of this fulltext: 30 Jan 2017 12:39


PURPOSE. Identification of sensitive biomarkers is essential to determine potential effects of emerging therapeutic trials for Stargardt disease. This study aimed to describe the natural history of late-onset Stargardt, and demonstrates the accuracy of retinal pigment epithelium (RPE) atrophy progression as an outcome measure. METHODS. We performed a retrospective cohort study collecting ...


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