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Study Protocol: A Pilot Study to Determine the Safety and Efficacy of Induction-Therapy, De Novo MPA and Delayed mTOR-Inhibition in Liver Transplant Recipients with Impaired Renal Function. PATRON-Study

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Schnitzbauer, Andreas A. ; Scherer, Marcus N. ; Rochon, Justine ; Sothmann, Johannes ; Farkas, Stefan A. ; Loss, Martin ; Geissler, Edward K. ; Obed, Aiman ; Schlitt, Hans J.
License: Creative Commons: Attribution 3.0
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Date of publication of this fulltext: 01 Feb 2017 13:02


Background Patients undergoing liver transplantation with preexisting renal dysfunction are prone to further renal impairment with the early postoperative use of Calcineurin-inhibitors. However, there is only little scientific evidence for the safety and efficacy of de novo CNI free "bottom-up" regimens in patients with impaired renal function undergoing liver transplantation. This is a ...


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