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A high-resolution physical map of human chromosome 11

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Qin, S. ; Nowak, N. J. ; Zhang, J. ; Sait, S. N. J. ; Mayers, P. G. ; Higgins, M. J. ; Cheng, Y. ; Li, L. ; Munroe, D. J. ; Gerhard, D. S. ; Weber, Bernhard H. F. ; Bric, E. ; Housman, D. E. ; Evans, G. A. ; Shows, T. B.
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Date of publication of this fulltext: 07 Apr 2017 08:16


The development of a highly reliable physical map with landmark sites spaced an average of 100 kbp apart has been a central goal of the Human Genome Project. We have approached the physical mapping of human chromosome 11 with this goal as a primary target. We have focused on strategies that would utilize yeast artificial chromosome (YAC) technology, thus permitting long-range coverage of hundreds ...


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