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Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane

Lukas, Karin, Stadtherr, Karin, Gessner, Andre , Wehner, Daniel, Schmid, Thomas, Wendel, Hans-Peter, Schmid, Christof and Lehle, Karla (2017) Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane. Materials 10 (335), pp. 1-12.

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Date of publication of this fulltext: 07 Apr 2017 06:33

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Other URL: http://www.mdpi.com/1996-1944/10/4/335

Dieser Artikel ist in einer Zeitschrift aus dem Directory of Open Access (DOAJ) publiziert.


Abstract

The surface of foils and vascular grafts made from a thermoplastic polycarbonate urethanes (PCU) (Chronoflex AR) were chemically modified using gas plasma treatment, binding of hydrogels-(1) polyethylene glycol bisdiamine and carboxymethyl dextran (PEG-DEX) and (2) polyethyleneimine (PEI)-and immobilization of human antithrombin III (AT). Their biological impact was tested in vitro under static ...

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Item type:Article
Date:24 March 2017
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ma10040335DOI
Keywords:VENTRICULAR ASSIST DEVICES; IN-VITRO; THROMBIN INHIBITOR; EXTRACORPOREAL-CIRCULATION; ENGINEERING APPLICATIONS; BLOOD COMPATIBILITY; PLATELET-ADHESION; NITRIC-OXIDE; ISO 10993-4; HEMOCOMPATIBILITY; polycarbonate urethane; thromboresistance; antithrombin III; anti-bacterial; hemocomaptibility
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35533
Owner only: item control page

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