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Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane

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Lukas, Karin ; Stadtherr, Karin ; Gessner, Andre ; Wehner, Daniel ; Schmid, Thomas ; Wendel, Hans-Peter ; Schmid, Christof ; Lehle, Karla
Date of publication of this fulltext: 07 Apr 2017 06:33


The surface of foils and vascular grafts made from a thermoplastic polycarbonate urethanes (PCU) (Chronoflex AR) were chemically modified using gas plasma treatment, binding of hydrogels-(1) polyethylene glycol bisdiamine and carboxymethyl dextran (PEG-DEX) and (2) polyethyleneimine (PEI)-and immobilization of human antithrombin III (AT). Their biological impact was tested in vitro under static ...


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