Plasma functionalization of polycarbonaturethane to improve endothelialization—Effect of shear stress as a critical factor for biocompatibility control

URN to cite this document:: urn:nbn:de:bvb:355-epub-356330
DOI to cite this document:: 10.5283/epub.35633

Lukas, Karin ; Thomas, U. ; Gessner, Andre

; Wehner, D. ; Schmid, Thomas ; Schmid, Christof ; Lehle, Karla

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Date of publication of this fulltext: 09 May 2017 09:12

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Abstract

Medical devices made of polycarbonaturethane (PCU) combine excellent mechanical properties and little biological degradation, but restricted hemocompatibility. Modifications of PCU might reduce platelet adhesion and promote stable endothelialization. PCU was modified using gas plasma treatment, binding of hydrogels, and coupling of cell-active molecules (modified heparin, anti-thrombin III ...