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Plasma functionalization of polycarbonaturethane to improve endothelialization—Effect of shear stress as a critical factor for biocompatibility control

Lukas, Karin, Thomas, U., Gessner, Andre , Wehner, D., Schmid, Thomas, Schmid, Christof and Lehle, Karla (2016) Plasma functionalization of polycarbonaturethane to improve endothelialization—Effect of shear stress as a critical factor for biocompatibility control. Journal of Biomaterials Applications 30, pp. 1417-1428.

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Date of publication of this fulltext: 09 May 2017 09:12

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Abstract

Medical devices made of polycarbonaturethane (PCU) combine excellent mechanical properties and little biological degradation, but restricted hemocompatibility. Modifications of PCU might reduce platelet adhesion and promote stable endothelialization. PCU was modified using gas plasma treatment, binding of hydrogels, and coupling of cell-active molecules (modified heparin, anti-thrombin III ...

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Item type:Article
Date:2016
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
10.1177/0885328215626072DOI
Keywords:Endothelial cell seeding, thrombogenicity, plasma treatment, hydrogel, polyurethane, sheer stress, biocompatibility
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35633
Owner only: item control page

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