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CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD

Scholl, H P, Fleckenstein, M, Fritsche, L G, Schmitz-Valckenberg, S, Göbel, A, Adrion, C, Herold, C, Keilhauer, C N, Mackensen, F, Mössner, A, Pauleikhoff, D, Weinberger, A W, Mansmann, U, Holz, F G, Becker, T and Weber, Bernhard H. F. (2009) CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. PLoS one 4 (10), e7418.

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Other URL: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007418


Abstract

Background Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been shown to confer significant risks for AMD; however, their role in disease progression and thus their potential relevance for ...

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Item type:Article
Date:2009
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1371/journal.pone.0007418DOI
19823576PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35860
Owner only: item control page

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