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Disease mechanisms and gene therapy in a mouse model for x-linked retinoschisis

Molday, L L, Min, S H, Seeliger, M W, Wu, W W, Dinculescu, A, Timmers, A M, Janssen, A, Tonagel, F, Hudl, K, Weber, Bernhard H. F. , Hauswirth, W W and Molday, R S (2006) Disease mechanisms and gene therapy in a mouse model for x-linked retinoschisis. Advances in experimental medicine and biology 572, pp. 283-289.

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X-linked retinoschisis (RS) is an inherited recessive macular degeneration that affects between 1 in 5000 and 1 in 25,000 males early in life (George et al., 1995; Sieving, 1998; Tantri et al., 2004). It is characterized by a loss in central vision, splitting of the retina with the appearance of spoke-like cystic cavities radiating from the parafoveal region of the retina, a loss in the b-wave of ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Humangenetik
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Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35865
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