Go to content
UR Home

The functional genetic variant Ile646Val located in the kinase binding domain of the A kinase anchoring protein 10 is associated with familial breast cancer

Wirtenberger, M, Schmutzhard, J, Hemminki, K, Meindl, A, Sutter, C, Schmutzler, R K, Wappenschmidt, B, Kiechle, M, Arnold, A, Weber, Bernhard H. F. , Niederacher, D, Bartram, C R and Burwinkel, B (2007) The functional genetic variant Ile646Val located in the kinase binding domain of the A kinase anchoring protein 10 is associated with familial breast cancer. Carcinogenesis 28 (2), pp. 423-426.

Full text not available from this repository.

at publisher (via DOI)

at PubMed


Abstract

Overexpression of cAMP-dependent protein kinase A (PKA) is a hallmark of the great majority of human cancers including breast cancer. A-kinase anchoring proteins (AKAPs) coordinate the specificity of PKA signalling by localizing the kinase to its subcellular sites. We tested the hypothesis whether the functional amino acid exchange Ile 646 Val , located in the kinase-binding domain of AKAP10, is ...

plus


Export bibliographical data



Item type:Article
Date:2007
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1093/carcin/bgl164DOI
16956908PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35921
Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons