L-9 and its receptor are predominantly involved in the pathogenesis of UC

URN to cite this document:: urn:nbn:de:bvb:355-epub-361652
DOI to cite this document:: 10.5283/epub.36165

Nalleweg, N. ; Chiriac, M. T. ; Podstawa, E. ; Lehmann, Christian

; Rau, Tilmann T. ; Atreya, R. ; Krauss, Ekaterina ; Hundorfean, G. ; Fichtner-Feigl, Stefan ; et, al. ; ;

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Date of publication of this fulltext: 08 Sep 2017 12:30

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Abstract

Objective Several pathogenic roles attributed over the past two decades to either T helper (Th) 1 or Th2 cells are increasingly becoming associated with interleukin (IL)-17 and most recently IL-9 signalling. However, the implication of IL-9 in IBD has not been addressed so far. Design We investigated the expression of IL-9 and IL-9R by using peripheral blood, biopsies and surgical samples. We ...