Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia

URN to cite this document:: urn:nbn:de:bvb:355-epub-374843
DOI to cite this document:: 10.5283/epub.37484

Monnier, Véronique ; Llorens, Jose

; Navarro, Juan

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Date of publication of this fulltext: 12 Jul 2018 08:13

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Abstract

Drosophila melanogaster has been for over a century the model of choice of several neurobiologists to decipher the formation and development of the nervous system as well as to mirror the pathophysiological conditions of many human neurodegenerative diseases. The rare disease Friedreich’s ataxia (FRDA) is not an exception. Since the isolation of the responsible gene more than two decades ago, the ...