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Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia

Navarro, Juan , Monnier, Véronique and Llorens, Jose (2018) Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia. International Journal of Molecular Sciences 19 (7), p. 1989.

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Date of publication of this fulltext: 12 Jul 2018 08:13

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Other URL: http://doi.org/10.3390/ijms19071989, http://www.mdpi.com/1422-0067/19/7/1989/xml


Abstract

Drosophila melanogaster has been for over a century the model of choice of several neurobiologists to decipher the formation and development of the nervous system as well as to mirror the pathophysiological conditions of many human neurodegenerative diseases. The rare disease Friedreich’s ataxia (FRDA) is not an exception. Since the isolation of the responsible gene more than two decades ago, the ...

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Item type:Article
Date:7 July 2018
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/ijms19071989DOI
Keywords:Drosophila melanogaster; Friedreich’s ataxia; frataxin; iron; oxidative stress; metal homeostasis; lipid metabolism; endoplasmic reticulum; genetic screens; drug screens
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 590 Zoological sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:37484
Owner only: item control page

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