Test Performance Characteristics of Anti-HEV IgG Assays Strongly Influence Hepatitis E Seroprevalence Estimates

URN to cite this document:: urn:nbn:de:bvb:355-epub-375192
DOI to cite this document:: 10.5283/epub.37519

Wenzel, Jürgen J.

; Preiss, Julia ; Schemmerer, Mathias

; Huber, Barbara ; Jilg, Wolfgang

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Date of publication of this fulltext: 13 Aug 2018 12:57

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Abstract

Hepatitis E virus (HEV) seroprevalences of 0.3%–53% were reported from industrialized countries. Because these estimates may be influenced by detection assays, this study compares 3 frequently used tests for HEV detection: the MP Diagnostics HEV immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA), the Axiom Diagnostics HEV IgG enzyme immunoassay (EIA), and the Mikrogen recomLine HEV ...