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Extended antigen sparing potential of AS03-adjuvanted pandemic H1N1 vaccines in children, and immunological equivalence of two formulations of AS03-adjuvanted H1N1 vaccines: results from two randomised trials

Launay, Odile, Duval, Xavier, Fitoussi, Serge, Jilg, Wolfgang, Kerdpanich, Angkool, Montellano, May, Schwarz, Tino F, Watanveerade, Veerachai, Wenzel, Jürgen J , Zalcman, Gerard, Bambure, Vinod, Li, Ping, Caplanusi, Adrian, Madan, Anuradha, Gillard, Paul and Vaughn, David W (2013) Extended antigen sparing potential of AS03-adjuvanted pandemic H1N1 vaccines in children, and immunological equivalence of two formulations of AS03-adjuvanted H1N1 vaccines: results from two randomised trials. BMC Infectious Diseases 13 (1).

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Date of publication of this fulltext: 13 Aug 2018 13:04

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Other URL: http://doi.org/10.1186/1471-2334-13-435


Abstract

Background Pandemic influenza vaccine manufacturing capacity and distribution agility is enhanced through the availability of equivalent antigen-sparing vaccines. We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines’ A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden (D-Pan), and Quebec (Q-Pan). Methods In two studies, 334 adults 18-60 years ...

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Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
10.1186/1471-2334-13-435DOI
Keywords:H1N1, Pandemic influenza vaccine, Influenza virus, Children, Adults, Persistence, Immunogenicity, Manufacturing capacity, Antigen dose reduction
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:37520
Owner only: item control page

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