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Extended antigen sparing potential of AS03-adjuvanted pandemic H1N1 vaccines in children, and immunological equivalence of two formulations of AS03-adjuvanted H1N1 vaccines: results from two randomised trials

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Launay, Odile ; Duval, Xavier ; Fitoussi, Serge ; Jilg, Wolfgang ; Kerdpanich, Angkool ; Montellano, May ; Schwarz, Tino F. ; Watanveerade, Veerachai ; Wenzel, Jürgen J. ; Zalcman, Gerard ; Bambure, Vinod ; Li, Ping ; Caplanusi, Adrian ; Madan, Anuradha ; Gillard, Paul ; Vaughn, David W.
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Date of publication of this fulltext: 13 Aug 2018 13:04


Background Pandemic influenza vaccine manufacturing capacity and distribution agility is enhanced through the availability of equivalent antigen-sparing vaccines. We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines’ A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden (D-Pan), and Quebec (Q-Pan). Methods In two studies, 334 adults 18-60 years ...


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