The Peripheral and Intratumoral Immune Cell Landscape in Cancer Patients: A Proxy for Tumor Biology and a Tool for Outcome Prediction

URN to cite this document:: urn:nbn:de:bvb:355-epub-376208
DOI to cite this document:: 10.5283/epub.37620

Schnell, Annette ; Schmidl, Christian ; Herr, Wolfgang ; Siska, Peter J.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 29 Aug 2018 12:04

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Abstract

Functional systemic and local immunity is required for effective anti-tumor responses. In addition to an active engagement with cancer cells and tumor stroma, immune cells can be affected and are often found to be dysregulated in cancer patients. The impact of tumors on local and systemic immunity can be assessed using a variety of approaches ranging from low-dimensional analyses that are ...