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Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects

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Munker, Stefan ; Gerken, Michael ; Fest, Petra ; Ott, Claudia ; Schnoy, Elisabeth ; Fichtner-Feigl, Stefan ; Wiggermann, Philipp ; Vogelhuber, Martin ; Herr, Wolfgang ; Stroszczynski, Christian ; Schlitt, Hans Jürgen ; Evert, Matthias ; Reng, Michael ; Klinkhammer-Schalke, Monika ; Teufel, Andreas
Date of publication of this fulltext: 27 Sep 2018 17:16


Background: 5-Fluorouracil (5FU), Folinic acid (FA), and Oxaliplatin (FOLFOX) or 5FU, FA, and Irinotecan (FOLFIRI) are standard regimens for palliative chemotherapy of metastatic colon cancer. Since data showing the influence of dose reduction in palliative treatment are rare, the objective of this single center, retrospective study was to further characterize the influence of dose reduction on ...


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