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Tigecycline in critically ill patients on continuous renal replacement therapy: a population pharmacokinetic study

Broeker, A., Wicha, S. G., Dorn, Christoph , Kratzer, Alexander Ludwig, Schleibinger, M., Kees, Frieder , Heininger, A., Kees, Martin G. and Häberle, H. (2018) Tigecycline in critically ill patients on continuous renal replacement therapy: a population pharmacokinetic study. Critical Care 22, p. 341.

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Date of publication of this fulltext: 08 Jan 2019 10:15

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Other URL: http://doi.org/10.1186/s13054-018-2278-4


Abstract

Background Tigecycline is a vital antibiotic treatment option for infections caused by multiresistant bacteria in the intensive care unit (ICU). Acute kidney injury (AKI) is a common complication in the ICU requiring continuous renal replacement therapy (CRRT), but pharmacokinetic data for tigecycline in patients receiving CRRT are lacking. Methods Eleven patients mainly with intra-abdominal ...

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Item type:Article
Date:2018
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Group Clinical Pharmacy (Dr. Dorn)
Identification Number:
ValueType
10.1186/s13054-018-2278-4DOI
Keywords:Tigecycline, Population pharmacokinetics, NONMEM, Dosing, Renal replacement therapy CVVHD, CVVHDF
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:38152
Owner only: item control page

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